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["Table 5. Association of T2DM and antidiabetic medications with high-risk, regional metastases and distant\nmetastases of prostate cancer  1"]
[null,"High risk 2",{"$nulls":3},"Regional metastases",{"$nulls":3},"Distant metastases"]
[null,"Controls (N)","Cases (N)","OR","95% CI","Controls (N)","Cases (N)","OR","95% CI","Controls (N)","Cases (N)","OR","95% CI"]
["T2DM "]
["no DM",{"v":24746,"d":"24,746"},{"v":5081,"d":"5,081"},"Ref",null,{"v":6772,"d":"6,772"},{"v":1398,"d":"1,398"},"Ref",null,{"v":15031,"d":"15,031"},{"v":3084,"d":"3,084"},"Ref"]
["T2DM",{"v":5333,"d":"5,333"},{"v":1011,"d":"1,011"},0.93,"(0.87-1.00)",{"v":1519,"d":"1,519"},282,0.9,"(0.78-1.04)",{"v":3232,"d":"3,232"},617,0.91,"(0.82-1.00)"]
[]
["Duration of T2DM (years)"]
["no DM",{"v":24746,"d":"24,746"},{"v":5081,"d":"5,081"},"Ref",null,{"v":6772,"d":"6,772"},{"v":1398,"d":"1,398"},"Ref",null,{"v":15031,"d":"15,031"},{"v":3084,"d":"3,084"},"Ref"]
["<1 ",257,67,1.28,"(0.97-1.68)",92,15,0.76,"(0.43-1.35)",158,44,1.33,"(0.95-1.87)"]
["1 - <5 ",{"v":1122,"d":"1,122"},224,0.99,"(0.85-1.14)",350,62,0.87,"(0.66-1.15)",712,117,0.8,"(0.65-0.97)"]
["5 - <10",{"v":1453,"d":"1,453"},281,0.95,"(0.83-1.08)",396,68,0.84,"(0.64-1.09)",816,158,0.87,"(0.73-1.04)"]
["10 - <20",{"v":1727,"d":"1,727"},316,0.9,"(0.80-1.02)",467,94,0.97,"(0.77-1.22)",{"v":1078,"d":"1,078"},201,0.89,"(0.76-1.04)"]
[20,774,123,0.77,"(0.63-0.94)",214,43,0.96,"(0.69-1.35)",423,97,1.06,"(0.84-1.32)"]
[]
["Duration of Insulin (years)"]
["no DM",{"v":24746,"d":"24,746"},{"v":5081,"d":"5,081"},"Ref",null,{"v":6772,"d":"6,772"},{"v":1398,"d":"1,398"},"Ref",null,{"v":15031,"d":"15,031"},{"v":3084,"d":"3,084"},"Ref"]
["0.5 - <3",509,80,0.77,"(0.60-0.98)",150,16,0.52,"(0.31-0.88)",317,64,0.9,"(0.68-1.19)"]
["3 - <5",291,46,0.85,"(0.63-1.16)",86,17,0.97,"(0.57-1.65)",197,35,0.83,"(0.58-1.20)"]
[5,971,169,0.86,"(0.72-1.01)",270,50,0.88,"(0.64-1.21)",588,120,0.96,"(0.78-1.18)"]
["Missing",{"v":3562,"d":"3,562"},713,null,null,{"v":1013,"d":"1,013"},199,null,null,{"v":2130,"d":"2,130"},398]
[]
["Duration of high-dose Metformin (years)"]
["no DM",{"v":24746,"d":"24,746"},{"v":5081,"d":"5,081"},"Ref",null,{"v":6772,"d":"6,772"},{"v":1398,"d":"1,398"},"Ref",null,{"v":15031,"d":"15,031"},{"v":3084,"d":"3,084"},"Ref"]
["0.5 - <3",{"v":1290,"d":"1,290"},235,0.89,"(0.77-1.03)",367,66,0.87,"(0.66-1.15)",761,134,0.84,"(0.69-1.02)"]
["3 - <5",508,97,0.96,"(0.77-1.20)",125,33,1.23,"(0.82-1.83)",291,55,0.89,"(0.67-1.20)"]
[5,408,95,1.19,"(0.94-1.50)",112,23,0.96,"(0.61-1.52)",231,58,1.25,"(0.93-1.68)"]
["Missing",{"v":3127,"d":"3,127"},584,null,null,915,160,null,null,{"v":1949,"d":"1,949"},370]
[]
["Duration of low-dose Metformin (years)"]
["no DM",{"v":24746,"d":"24,746"},{"v":5081,"d":"5,081"},"Ref",null,{"v":6772,"d":"6,772"},{"v":1398,"d":"1,398"},"Ref",null,{"v":15031,"d":"15,031"},{"v":3084,"d":"3,084"},"Ref"]
["0.5 - <3",{"v":1966,"d":"1,966"},385,0.97,"(0.86-1.09)",552,101,0.89,"(0.71-1.12)",{"v":1200,"d":"1,200"},223,0.86,"(0.74-1.00)"]
["3 - <5",891,152,0.85,"(0.72-1.02)",228,48,1,"(0.73-1.38)",515,87,0.81,"(0.64-1.02)"]
[5,428,86,0.97,"(0.76-1.23)",124,33,1.44,"(0.97-2.15)",292,54,0.87,"(0.65-1.17)"]
["Missing",{"v":2048,"d":"2,048"},388,null,null,615,100,null,null,{"v":1225,"d":"1,225"},253]
[]
["Duration of SU (years)"]
["no DM",{"v":24746,"d":"24,746"},{"v":5081,"d":"5,081"},"Ref",null,{"v":6772,"d":"6,772"},{"v":1398,"d":"1,398"},"Ref",null,{"v":15031,"d":"15,031"},{"v":3084,"d":"3,084"},"Ref"]
["0.5 - <3",559,81,0.7,"(0.55-0.88)",151,29,0.89,"(0.58-1.36)",349,60,0.83,"(0.62-1.09)"]
["3 - <5",302,54,0.85,"(0.63-1.15)",78,15,0.95,"(0.53-1.70)",187,29,0.65,"(0.43-0.98)"]
[5,469,69,0.74,"(0.57-0.96)",128,22,0.81,"(0.51-1.28)",285,63,1.07,"(0.81-1.42)"]
["Missing",{"v":4003,"d":"4,003"},807,null,null,{"v":1162,"d":"1,162"},216,null,null,{"v":2411,"d":"2,411"},465]
["1 The results were adjusted for CCI, education level, civil status and the age at year of PCa onset. "]
["2 Cases in “high risk” only refer to PCa men at T3a or T4 stage, whose PSA ≥ 20ng/ml or Gleason Score ≥ 8, without regional metastases and distant metastases.  "]